Nuclear Receptors A Practical Approach 2nd Edition
-60%
Availability: In Stock

Nuclear Receptors A Practical Approach 2nd Edition

SKU: 9780191565922

Original price was: $61.99.Current price is: $24.99.

Access Nuclear Receptors A Practical Approach 2nd Edition Now. Discount up to 90%

Categories: ,

Additional information

Full Title

Nuclear Receptors A Practical Approach 2nd Edition
Author(s)

Didier Picard
Edition

2nd Edition
ISBN

9780191565922, 9780199637423, 9780199637430
Publisher

OUP Oxford
Format

PDF and EPUB

Description

The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new.

Related products