Cell Polarity and Subcellular RNA Localization 1st Edition
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Cell Polarity and Subcellular RNA Localization 1st Edition

SKU: 9783540400257

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Additional information

Full Title

Cell Polarity and Subcellular RNA Localization 1st Edition
Author(s)

Dietman Richter
Edition

1st Edition
ISBN

9783540400257, 9783540411420
Publisher

Springer
Format

PDF and EPUB

Description

Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of mRNA and viral RNA as another example of subcellular RNA kinesis.

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