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Intracellular Calcium-Dependent Proteolysis 1st Edition

SKU: 9781351090711

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Additional information

Full Title

Intracellular Calcium-Dependent Proteolysis 1st Edition

Author(s)

Ronald L. Mellgren

Edition

1st Edition

ISBN

9781351090711, 9781315894713, 9781351073813, 9781351082266, 9781351099165

Publisher

CRC Press

Format

PDF and EPUB

Description

Intracellular Calcium-Dependent Proteolysis explains what is now known about calpains, which are intracellular, non-lysosomal enzymes involved in intracellular protein catabolism. The book provides a comprehensive overview of topics ranging from the molecular biology of the calpains and their specific inhibitor protein (calpastatin) to physiologic and pathologic consequences of the presence of this proteolytic system in many model cells and tissues. Several theoretical functions of the calpains are discussed, including their potential roles in muscle protein turnover, platelet activation, membrane fusion, and synaptic plasticity. Intracellular Calcium-Dependent Proteolysis is a valuable source of information for researchers and students interested in the regulation of intracellular protein catabolism and the general effects of Ca2+ on cell function.